Back to the future: new study could lead to bumper crops

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By Jessica Fagan, ANU,  July 14, 2020

Research led by scientists at the ARC Centre for Translational Photosynthesis at The Australian National University (ANU), could lead to major improvements in crop production.

The study shows a new way to help study and ramp up photosynthesis.

It looks specifically at Rubisco activity – a crucial part of the process according to co-author Professor Spencer Whitney, from the ARC Centre of Excellence for Translational Photosynthesis.

“Rubisco is an enzyme involved in the first step of carbon fixation – it starts the conversion of carbon dioxide into plant sugars,” he said.

“But compared to other enzymes, Rubisco is considered a pretty slow, inefficient catalyst.

“Many enzymes can process hundreds to thousands of molecules per second, but rubisco can only get through 2-5 cycles per second.

“For this reason, it’s long been recognised as a good target for improving photosynthesis – it’s a puzzle scientists have been looking at for decades.”

In plants Rubisco is made up of 16 proteins – eight large and eight small subunits. Until now scientists have only been able to tinker with one subunit at a time.

“We’ve now turned back the clock a billion years to rectify this limitation,” Professor Whitney said.

“By reapplying the genome design of the bacterial ancestors of chloroplasts we can now play around with all the components of Rubisco simultaneously.

“This is crucial. To ramp up its activity you have to make changes to all the components.”

It could mean big gains for canola and potato crop in particular.

“We know we can already tinker with Rubisco activity in these crops, so it’s a great place to start,” Professor Whitney said.

“This is the just the first step – this technology could eventually deliver something much bigger in the not so distant future.”

The research has been published in the journal The Plant Cell. Journalists who want to link to the article, can use the following reference and doi:

Martin-Avila, E., Lim, Y.-l., Birch, R., Dirk, L.M.A., Buck, S., Rhodes, T., Sharwood, R., Kapralov, M.V. and Whitney, S.M. (2020). Modifying Plant Photosynthesis and Growth via Simultaneous Chloroplast Transformation of Rubisco Large and Small Subunits. Plant Cell DOI:

Click here to read the original article at The ANU Newsroom